Dr. Sascha Schäuble

Peer Aramillo Irizar, Sascha Schäuble, Daniela Esser*, Marco Groth, Christiane Frahm, Steffen Priebe, Mario Baumgart, Nils Hartmann, Shiva Marthandan, Uwe Menzel, Julia Müller, Silvio Schmidt, Volker Ast, Amke Caliebe, Rainer König, Michael Krawczak, Michael Ristow, Stefan Schuster, Alessandro Cellerino, Stephan Diekmann, Christoph Englert, Peter Hemmerich, Jürgen Sühnel, Reinhard Guthke, Otto W. Witte, Matthias Platzer, Eytan Ruppin & Christoph Kaleta, Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly, Nature Communications, 9, Article number: 327 (2018), doi:10.1038/s41467-017-02395-2

Sebastian Weis, Ana Rita Carlos, Maria Raquel Moita, Sumnima Singh, Birte Blankenhaus, Silvia Cardoso, Rasmus Larsen, Sofia Rebelo, Sascha Schäuble, Laura Del Barrio, Gilles Mithieux, Fabienne Rajas, Sandro Lindig, Michael Bauer, Miguel P. Soares, Metabolic Adaptation Establishes Disease Tolerance to Sepsis, Cell 169 (7), 1263-1275. e14, doi: 10.1016/j.cell.2017.05.031
Sascha Schäuble, Anne-Kristin Stavrum, Mathias Bockwoldt, Pål Puntervoll and Ines Heiland, SBMLmod: A Python-Based Web Application and Web Service for Efficient Data Integration and Model Simulation, BMC Bioinformatics 18 (1), 314

Piero Dalle Pezze, Stefanie Ruf, Annika G. Sonntag, Miriam Langelaar-Makkinje, Philip Hall, Alexander M. Heberle, Patricia Razquin Navas, Karen van Eunen, Regine C. Tölle, Jennifer J. Schwarz, Heike Wiese, Bettina Warscheid, Jana Deitersen, Björn Stork, Erik Fäßler, Sascha Schäuble, Udo Hahn, Peter Horvatovich, Daryl P. Shanley & Kathrin Thedieck, A systems study reveals concurrent activation of AMPK and mTOR by amino acids, Nat Comm, doi:10.1038/ncomms13254
Robert Häsler, Raheleh Sheibani-Tezerji, Anupam Sinha, Matthias Barann, Ateequr Rehman, Daniela Esser, Konrad Aden, Carolin Knecht, Berenice Brandt, Susanna Nikolaus, Sascha Schäuble, Christoph Kaleta, Andre Franke, Christoph Fretter, Werner Müller, Marc-Thorsten Hütt, Michael Krawczak, Stefan Schreiber, Philip Rosenstiel, Uncoupling of mucosal gene regulation, mRNA splicing and adherent microbiota signatures in inflammatory bowel disease. Gut. Epub ahead of Print, doi:10.1136/gutjnl-2016-311651
Juliane Gebauer, Christoph Gentsch, Johannes Mansfeld, Kathrin Schmeißer, Silivo Waschina, Susanne Brandes, Lukas Klimmasch, Nicola Zamboni, Kim Zarse, Stefan Schuster, Michael Ristow, Sascha Schäuble, Christoph Kaleta, A Genome-Scale Database and Reconstruction of Caenorhabditis elegans Metabolism. Cell Syst, 2 (5), 312-322. doi: 10.1016/j.cels.2016.04.017

Saheed Imam, Sascha Schäuble, Jacob Valenzuela, Adrián López García de Lomana, Warren Carter, Nathan Price, Nitin Baliga, A refined genome-scale reconstruction of Chlamydomonas metabolism: A platform for systems-level analyses. The Plant Journal, 84 (6), 1239-1256
Saheed Imam, Sascha Schäuble, Aaron N. Brooks, Nitin S. Baliga and Nathan Price. Data-driven integration of genome-scale regulatory and metabolic network models. Frontiers in Microbiology, 6:409, doi: 10.3389/fmicb.2015.00409
Adrián López García de Lomana, Sascha Schäuble, Jacob Valenzuela, Saheed Imam, Warren Carter, Damla D. Bilgin, Christopher B. Yohn, Serdar Turkarslan, David J. Reiss, Monica V. Orellana, Nathan D. Price, Nitin S. Baliga, Transcriptional program for nitrogen starvation-induced lipid accumulation in Chlamydomonas reinhardtii. Biotechnology for Biofuels, 8:207
Maria T. E. Prauße, Sascha Schäuble, Reinhard Guthke, Stefan Schuster. Computing the various pathways of penicillin synthesis and their molar yields. Biotechnol Bioeng., 84, 1239-1256

Christoph Kaleta, Sascha Schäuble, Ursula Rinas and Stefan Schuster. Metabolic costs of amino acid and protein production in Escherichia coli. Biotechnol J. 8(9):1105-114. doi: 10.1002/biot.201200267
Sascha Schäuble, Anne Kristin Stavrum, Pal Puntervoll, Stefan Schuster and Ines Heiland. Effect of substrate competition in kinetic models of metabolic networks. FEBS Lett, 587(17):2818-2824. doi: 10.1016/j.febslet.2013.06.025.2013
Georg Fuellen, Melanie Boerries, Hauke Busch, Aubrey de Grey, Udo Hahn, Thomas Hiller, Andreas Hoeflich, Ludger Jansen, Georges E Janssens, Christoph Kaleta, Anne C Meinema, Sascha Schäuble, Andreas Simm, Paul N Schofield, Barry Smith, Juergen Sühnel, Julio Vera, Wolfgang Wagner, Eva C Wönne, Daniel Wuttke, In Silico Approaches and the Role of Ontologies in Aging Research, Rejuvenation Res. 16(6):540-6, doi: 10.1089/rej.2013.1517

Sascha Schäuble,Karolin Klement, Shiva Marthandan, Sandra Münch, Ines Heiland, Stefan Schuster, Peter Hemmerich and Stephan Diekmann. Quantitative model of cell cycle arrest and cellular senescence in primary human fibroblasts. PLoS One, 7(8):e42150, 2012. doi: 10.1371/journal.pone.0042150

Sascha Schäuble, Ines Heiland, Olga Voytsekh, Maria Mittag, and Stefan Schuster. Predicting the Physiological Role of Circadian Metabolic Regulation in the Green Alga Chlamydomonas reinhardtii. PLoS One, 6(8):e23026. doi: 10.1371/journal.pone.0023026
Sascha Schäuble, Stefan Schuster, and Christoph Kaleta. Hands-on metabolism: Analysis of complex biochemical networks using elementary flux modes. Meth. Enzymol. 500, 437-456

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